ICanHasCheezburger
Funny cat pictures

IHasAHotDog
Funny dog pictures

roflrazzi
Lol Celebs

totallylookslike
Totally Looks Like

punditkitchen
Lol Politics Fun

graphjam
Humor in Charts and Graphs

onceuponawin
Epic Wins from when we were kids

failblog
Epic Fail Picture

xkcd
Safe Haven from Velociraptors

garfieldminusgarfield
Removing Garfield from the Garfield

phdcomics
Life (or the lack thereof) in Academia

dilbertcomic
Satirical office humor

wulffmorgenthaler
Humoristic social commentary on life